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Molecular Epidemiology and Environmental Epigenetics  

Grafico

The Center of Molecular Epidemiology and Environmental Epigenetics (COME) is devoted to the study of the mechanisms through which molecular and environmental  factors concur (interact) in determining health and disease  in human subjects and populations.  Our research emphasizes the role of the environment we live in as a potential determinant of the risk of complex, multifactorial human diseases. Research programs are mainly focused on the comprehension of epigenetic mechanisms such as DNA methylation, histone modifications and microRNA expression.

 

MAIN INSTRUMENTS

  • 2 PyroMark MD System (Pyrosequencing, Inc.)
  • 1 Openarray QuantStudio™ 12K Flex (Applied Biosystem)
  • 1 Real Time PCR AB 7900 HT (Applied Biosystem)
  • 7 PCR
  • 1 Robot 8-Channel Liquid Handler (Microlab Starlet, Hamilton Robotics)
  • 1 Optima Max-XP tabletop ultracentrifuge (Beckman Coulter)
  • 1 Maxwell® 16 automated sample purification system (Promega)
  • 1 Nanosight LM10-HS (Nanosight Ld)
  • 1 MACSQuant Analyzer for Flow Cytometry (Miltenyi Biotec, Germany)
  • 1 Automax Pro cell separator (Miltenyi Biotec, Germany)
  • 1 xCELLigence System for real-time cell analysis (Roche)
  • 1 cell colture room (equipped with a laminar flow hood, AHSI and two incubators, Innova)
  • 1 optical microscope (Leica)
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